Pollution
Atopic dermatitis and pollution being its cause have long been discussed until finally, ayl-hydrocarbon receptors and its role in triggering itch starch responses came under study. The environment is the home for many gases and pollutants, and these pollutants are responsible for triggering many diseases like asthma and multiple skin infections. Recent studies have suggested many air pollutants and environmental compounds to be toxic and dangerous. Volatile organic compounds, tobacco smoke, nitrogen oxide, toluene, formaldehyde have shown to be a risk factor in the development of atopic dermatitis. These compounds induce oxidative stress that can affect the skin or can cause immune dysregulation. Other than oxidative stress, these pollutants can activate the transcription factor AhR (aryl hydrocarbon receptors). This transcription factor AhR has identified to target a gene that results in epidermal innervation and inflammation. There is still more research being performed to understand how environmental pollution contributes to the development of atopic dermatitis and further research on, but the studies that have been performed and conducted until now have strongly suggested a relation between pollution and the onset of atopic dermatitis. Moe understanding, better knowledge, and better strategy are required to prevent and manage atopic dermatitis.