Spontaneous Mutation
Although hemophilia is a genetic disorder, not always, this disease develops as a result of inheritance. Sometimes mother and father may not be carrying the defective gene, and the child born with the bleeding disorder has no family history of hemophilia. This condition happens as a result of spontaneous mutation in the genes of the baby. Many factors may lead to the change in a DNA sequence, which alters the genes and becomes the reason for the onset of hemophilia. Studies reported that almost 30% of cases of hemophilia are due to spontaneous mutations in the genes.