Tests Performed On The Biopsy Sample
Sample after collection is passed through many clinical trials to confirm the diagnosis. These tests are the following:
Cytogenetics: Chromosome contains all the genetic information. As we know that the possible cause of MDS is a genetic mutation, so this test checks for any abnormality in the chromosomes. This test usually takes 14 to 21 days.
Histochemistry: This test measures the blast cells in the bone marrow and allows the pathologist to detect abnormal cells in the sample that may be the cause of bone marrow dysfunction.
Flow cytometry: This test uses particular proteins to treat a bone marrow sample. These proteins, which are antibodies, stick to some other proteins that are present only in abnormal cells.
Genetic tests: These tests measures some unique genetic characteristics of bone marrow cells.
Fluorescent in situ hybridization:
This test uses special fluorescent dyes that stick only to specific genes. This test usually takes about 2 to 3 days.
Polymerase chain reaction:
PCR is a susceptible test that can detect the very minute amount of abnormal cells present in the sample.