Slow Growth
Sickle cell anemia causes a child to have slow growth, pale complexion, delayed puberty, tire easily, or shortness of breath.
Sickle cell trait
In sickle cell trait, red blood cells are not fragile and do not break easily. Keep in consideration that Sickle cell trait does not cause painful crises. Sickle cell trait undergoes very strenuous exercise that also causes severe dehydration.