Organ Damage
Sickle cell anemia blocks the blood flow and oxygen to organs oxygen. In this severe condition, blood is chronically low in oxygen. However, the lack of oxygen-rich blood damages the nerves and organs. Some of the major organs include liver kidneys and spleen.
Gallstones
The breakdown of red blood cells can lead to the production of a substance called bilirubin. However, a high level of bilirubin in the body can lead to gallstones.