Common Causes Of Uterine Fibroids
Doctors do not know the exact cause of uterine fibroids but clinical experience and research point that hormonal imbalance, genetic mutations, and excess body fat might contribute to the development of uterine fibroids. Doctors believe the idea that the uterine fibroids grow from a stem cell in the smooth muscular tissue of the uterus which is known as the myometrium. [4]
A single cell in the myometrium divides itself repeatedly and eventually results in a rubbery and firm material that differs from the surrounding tissues of the uterus. The growth patterns in each uterine fibroid vary greatly as they may grow rapidly or slowly. Sometimes, the uterine fibroids remain the same size as of their originating stem in the uterine wall. Also, certain fibroids in the uterus go through growth spurts and some might shrink on their own. Many uterine fibroids that remain persistent in growth during pregnancy tend to disappear or shrink after pregnancy because the uterus comes back to its normal size. [5]
Following are some causes of uterine fibroids in women:
Genetic changes
Many fibroids develop in the uterus as a result of certain changes in genes that are not normal. The genetic material present within the fibroids growing in the uterus differ from the genetic material present in the normal muscle cells of the uterus.