Wide Hands and Feet
Problems in the feet and hands are the biggest indication of Down syndrome and a common physical trait, appearing in a large number of people with Down syndrome. Patients with Down syndrome typically have only one crease in their palms, while the rest of the population contains two. Another distinctive sign of people with Down syndrome is that their feet are smaller, having a large space between the big toe and other toes. It’s important to note that these signs and symptoms do not determine overall health, but they indicate Down syndrome.