Anemia
Anemia is a common presentation in children with hemolytic uremic syndrome and is associated with a worse outcome. With hemolytic uremic syndrome, bacteria in the digestive tract splits red blood cells hemoglobin into by-products that damage kidneys and cause anemia.
The anemia of hemolytic uremic syndrome may be normocytic or hypochromic. The low serum iron level, low total iron-binding capacity, the high serum soluble transferrin receptor level and the reduction in the percentage of serum lactate dehydrogenase (LDH) released into plasma, indicates that in hemolytic uremic syndrome, both red cell destruction and decreased erythropoiesis are contributing to the anemia.