Mechanisms Underlying Development Of Pancreatic Cancer
Like all cancers, the root cause of the disruption is unclear. However, it can be seen that underling pancreatic illness, like chronic pancreatitis has increased chances of developing into a malignant tumor. Recurrent attacks of pancreatitis, which is the inflammation of the pancreas can result in cells accumulating genetic mutations. These mutations then unleash the malignant potential of cells. The cellular checkpoints which ensure proper multiplication of cells, are lost. The cells not only increase in number, but also fail to differentiate. This means that the new cells are unable to be functional.