Causes Of Type 1 Diabetes
Insulin is a hormone that aids in moving glucose or sugar into your body’s tissues. The cells utilize it as fuel. The harm to beta cells from type 1 diabetes falls the process off. Glucose does not get into your cells because insulin is not present there to perform. Instead, it forms up in your cells and your blood starves. This might lead to high blood sugar that will eventually lead to
Dehydration: When there is excessive sugar in the blood, you urinate more frequently. That is the way your body is getting rid of all of it. A huge amount of water is removed with that urine, leading your body to be in the condition of dehydration.
Weight loss: The glucose that removes whenever you urinate takes calories with it. Therefore, that’s why several people with increasing blood sugar lose their weight rapidly. Dehydration also plays an important role.
Diabetic ketoacidosis (DKA): If the body cannot attain sufficient glucose for fuel, it turns down the fat cells instead. This forms chemicals known as ketones. The liver secretes the sugar it accumulates to help out. But the body cannot utilize it without insulin, so it forms up in your bloodstream, along with the acid form up is called ketoacidosis and might be life-threatening if left untreated.
Harm to your body: by the time, high levels of glucose in the blood might be harmful for small blood vessels and the nerves in your kidneys, eyes and heart. They might also make you more likely to have atherosclerosis, hardening of arteries that might lead to strokes and heart attack.
There is no other way to cure type 1 diabetes. Doctors don’t know all such things that might lead to it. But they do know that your genes play a significant role. They also know that you can have type 1 diabetes when something surrounds you, such as a virus, narrates your immune system to go after the pancreas. Many people have type 1 diabetes with symptoms of such an attack also known as autoantibodies. They are there in approximately who are experiencing situation when their blood sugar is increasing. Type 1 diabetes might occur along with other autoimmune diseases such as vitiligo and Graves ’ disease.
The exact reason for type 1 diabetes is still not known. Mostly, the body’s immune system that typically fights harmful viruses and bacteria mistakenly damages the insulin forming (islets or islet of Langerhans) cells present in the pancreas.
Other possible reasons consist of
- Exposure to other environmental factors and viruses
- Genetics
Insulin Role
Once an essential number of islet cells are destroyed, you will form little or no insulin. Insulin is a hormone that occurs from a gland present below and behind the stomach (pancreas).
- Insulin reduces the sugar amount in the bloodstream
- The pancreas releases insulin into your bloodstream
- As the blood sugar level gets low, so does the release of insulin from the pancreas
- Insulin circulates, letting sugar to enter into your cells
Glucose Role In The Body
Glucose or a sugar is a chief source of energy for the body cells that form up other tissues and muscles.
- Your liver stores the glucose in the form of glycogen
- Glucose occur from two major sources; from your liver and food
- Sugar absorbs into your bloodstream, where it allow the cells to enter with aid of insulin
- When the glucose level reduces, such as when you didn’t eat in while, the liver turns down the glycogen stores into the glucose to maintain your glucose levels in the normal range
In type 1 diabetes, there is no insulin present to let the glucose enter into the cells, so sugar forms up in the bloodstream. This might lead to life-threatening conditions. Type 1 diabetes happens when the immune system, the system of the body for fighting against infections, destroys and attacks the insulin forming beta-cells of the pancreas. Scientists might assume type 1 diabetes is led by environmental factors like viruses and genes that may trigger such disease. Studies like TrialNet are performing to mention the reason for type 1 diabetes and other occurring ways to slow and cure the disease. Type 1 diabetes might lead to any type of illness consisting of the common cold.
Viral infection: Researchers think that type 1 diabetes might be stimulated by a virus like the cold or common flu. Most occurring, type 1 diabetes appears on in the weeks ensuing a viral infection like rubella, measles, encephalitis, Epstein Barr, mumps, cytomegalovirus, polio and influenza etc.
Removal or injury of the pancreas: Quiterarely, type 1 diabetes might be stimulated by trauma or injury to the pancreas. Whenever pancreas is removed surgically, the body also lowers the ability to form insulin that then leads to type 1 diabetes.
When type 1 diabetes is stimulated by a virus, someone leading to autoimmune situations might form an autoimmune response. This means that the immune system of the body will begin to attack its own cells. In type 1 diabetes, the body starts attacking the beta cells in the pancreas that might lead to producing insulin. Researchers do not know the accurate reason for type 1 diabetes. It is viewed to be an autoimmune reaction, where the body starts attacking the cells present in the pancreas that form insulin mistakenly, per the Centers for Disease Control and Prevention (CDC). But the scientists do not completely understand why this occurs.
Some people might be responsible for forming such a condition because of genetics, according to the American Diabetes Association (ADA). While, other people might have it because of environmental factors like diet. Viruses might also be a part of such a condition. Sometimes a combination of these reasons will trigger such conditions. Some hormonal disorders might lead to the body to form a lot of certain hormones that sometimes are the reason for diabetes and insulin resistance. (4)
- Acromegaly happens when the body forms a lot of growth hormone.
- Cushing’s syndrome might occur when the body forms a lot of cortisol sometimes known as the stress hormone