Gout
Gout is a painful inflammatory condition caused by increased uric acid levels in the body. It is a type of arthritis. Gout can affect the entire body, causing severe pain that can last for days. It is common to experience these symptoms in the big toe and the feet, but gout can also affect other body parts, such as the ankles. The symptoms show up in flare-ups and are usually accompanied by fatigue and constitutional symptoms.
As mentioned above, it is caused by high levels of uric acid, which occur when the body has excess purines, metabolic overproduction of uric acid, or elimination defect. The uric acid forms crystals in the ankle and starts causing ankle pain. Rubbing against the joint, the crystals will also trigger inflammation, which contributes to the pain sensation.
Other symptoms of gout are nausea and vomiting. If left untreated, gout can lead to other health complications, such as deformation of the articulation. Gout symptoms come and go, but they become more frequent and severe if you are not treated.