Emphysema : Definition, Symptoms, Causes, Diagnosis, Types, Stages, Life Expectancy, Pathophysiology, Medications, Complications and Treatment

Centrilobular Emphysema

Centrilobular emphysema
Centrilobular emphysema

Centribular emphysema primarily damages the upper portion of pulmonary lobes in the lungs. Centrilobular emphysema’s major characterization is that the damage to a patient’s respiratory passage ways, medically known as bronchioles. The bronchioles or the passage ways allow the airflow from a person’s nose and mouth to their lungs. The damage happening to the alveolar sacs typically initiates in the central area of the lungs and slowly spread it towards the outside of the structure of lungs. Centrilobular emphysema tends to result in most harm in the upper alveolar sacs of the lungs. The pathological mechanism of centrilobular emphysema usually initiates near the central portion of the secondary pulmonary lobule locating in the area of the proximanl respiratory bronchiole. Selective destruction happens in the lungs which is a characteristic apposition of the emphysematous and normal lung. The resulting region of destruction surrounds the normal tissues and allows the spread of key structural lesions which are visible to a naked eye. The spread of key structural lesions in surrounding lung tissues is medically known as the emphysematous space.