Angiotensin-Converting Enzyme Inhibitors:
Angiotensin-converting enzymes and angiotensin ll receptor blocker aid in lowering the blood pressure, treatment of heart failure, lowering the illness, and death rate due to the cardiac arrest, to stop the development of renal disease in non-diabetic patients. In the walls of afferent arterioles of the kidneys, juxtaglomerular cells rennin enzyme secretes. The secretion of renin is affected by internal and external factors, like renal pressure, sodium, angiotensin, potassium, prostaglandins. Reduced sodium and chloride in the misal tubule releases renin.
Angiotensinogen present in the blood reacts with the rennin, and angiotensin l is produced, by the magic o angiotensin-converting enzyme it is transformed to angiotensin ll. The coexistence of disease and medications to treat the disease ACE inhibitors and ARBs can lead to the uncontrolled discharge of potassium causing hyperkalemia.