Genetic Syndromes
Any inherited condition with genetic mutation predisposes the patient to cancer. These genetic conditions may have been passed down from the parents to the children, or may be a result of any complication in the fetal life
- Lynch syndrome: the patient with this genetic mutation have a 3.7% chance of developing pancreatic cancer. The already present genetic mutation by birth increase the error rate of replication every time the cell divides.
- Familial pancreatitis: this condition is characterized by recurrent case of pancreatitis in a family, with no or poor evidence of the general causes of pancreatitis. This is because of certain mutation that runs I the family, predisposing individuals to pancreatitis. Over time, the same mutation may trigger new mutations to give rise to cancer.
- Peutz-Jeghers syndrome: this genetic condition increases the chance of pancreatico-biliary caner along with other tumors of the digestive tract.