Tretinoin cream
Tretinoin cream or Retin A cream consists of vitamin A which increases the efficiency of the topical cream to reduce the appearance of dark patches. You can use tretinoin cream alone to get the best results. There might be some side effects after using the tretinoin cream for the first time, which might include dry skin, scaling of the skin, and mild irritation. As it is common with every skin lightening treatment that there is some irritation, but the results come after a few applications. There is a potentially benefiting effect of vitamin A creams on the melasma patches, and there is plenty of topical creams available on the market with different concentrations.