Diabetes
Diabetes is a chronic condition seen in the patients that cannot produce enough amount of insulin due to Inability of pancreases to produce enough insulin in the body which results in increased blood glucose level also known as hyperglycemia. Trigger finger has seen to be a common complication in diabetes patient, and therefore it is being considered as a significant cause of trigger finger. Recent reports have shown major distress on trigger digits in diabetic patients, especially in long-standing diabetes. The incidence of trigger finger is between 2% and 3% in the general population while it’s up to 10% in diabetic patients. Also, the patients who have diabetes from many years are more likely to develop trigger finger. It is assumed that in the patients having persistently elevated blood sugar level results in the connective tissue to become glycated, which means an irreversible bond is created between the glucose and protein in the tissues that have a damaging effect on it. A cross-linking between collagen molecules is created due to hyperglycemia which results in collagen buildup in the tendon sheath around the flexor tendons, which increases the chances of trigger finger. However, further research is being performed to find the major causes of trigger finger related to diabetes.